E-ISSN 3049-0472 | ISSN 3107-3832
 

Case Report 


Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases

Ajitesh Kaplish, Arvinder Pal Singh, Jyotsana Sikri, Aman Dhiman, Shefali ..


Abstract
The management of open apex teeth poses clinical challenges in endodontics. Platelet-Rich Fibrin (PRF) and Mineral Trioxide Aggregate (MTA) offer promising outcomes for such teeth. PRF serves as a biologically active scaffold promoting tissue regeneration, while MTA provides an effective apical seal. Combined, they facilitate apexification, enhance healing, and improve prognosis in immature, non-vital teeth. This approach ensures biocompatibility and clinical success.

Key words: Regenerative endodontics, Mineral trioxide aggregate, Platelet rich fibrin


 
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How to Cite this Article
Pubmed Style

Kaplish A, Singh AP, Sikri J, Dhiman A, . S. Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. JHSPE. 2025; 5(1): 53-59. doi:10.5455/jhspe.20250610083102


Web Style

Kaplish A, Singh AP, Sikri J, Dhiman A, . S. Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. https://www.jhspe.in/?mno=263714 [Access: September 23, 2025]. doi:10.5455/jhspe.20250610083102


AMA (American Medical Association) Style

Kaplish A, Singh AP, Sikri J, Dhiman A, . S. Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. JHSPE. 2025; 5(1): 53-59. doi:10.5455/jhspe.20250610083102



Vancouver/ICMJE Style

Kaplish A, Singh AP, Sikri J, Dhiman A, . S. Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. JHSPE. (2025), [cited September 23, 2025]; 5(1): 53-59. doi:10.5455/jhspe.20250610083102



Harvard Style

Kaplish, A., Singh, . A. P., Sikri, . J., Dhiman, . A. & ., . S. (2025) Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. JHSPE, 5 (1), 53-59. doi:10.5455/jhspe.20250610083102



Turabian Style

Kaplish, Ajitesh, Arvinder Pal Singh, Jyotsana Sikri, Aman Dhiman, and Shefali .. 2025. Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. Journal of Health Sciences and Professions Education, 5 (1), 53-59. doi:10.5455/jhspe.20250610083102



Chicago Style

Kaplish, Ajitesh, Arvinder Pal Singh, Jyotsana Sikri, Aman Dhiman, and Shefali .. "Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases." Journal of Health Sciences and Professions Education 5 (2025), 53-59. doi:10.5455/jhspe.20250610083102



MLA (The Modern Language Association) Style

Kaplish, Ajitesh, Arvinder Pal Singh, Jyotsana Sikri, Aman Dhiman, and Shefali .. "Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases." Journal of Health Sciences and Professions Education 5.1 (2025), 53-59. Print. doi:10.5455/jhspe.20250610083102



APA (American Psychological Association) Style

Kaplish, A., Singh, . A. P., Sikri, . J., Dhiman, . A. & ., . S. (2025) Regenerative endodontic procedure for management of open apices in permanent incisors using Platelet rich fibrin (PRF) and mineral trioxide aggregate (MTA) - A descriptive report of two cases. Journal of Health Sciences and Professions Education, 5 (1), 53-59. doi:10.5455/jhspe.20250610083102